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Search Term: epidermal+growth+factor
Technologies
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Peptides targeting EGFL7, a critical player in angiogenesis
Background:Epidermal growth factor-like 7 (EGFL7) is an endothelial cell secreted protein whose expression is restricted to actively remodeling vascular endothelium. It is critical for vascular tube formation during angiogenesis through localizing to the extracellular matrix (ECM) at the basal surface of endothelial cells and promoting endothelial cell...
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EGFR antagonist-mediated prevention of post myocardial infarction ruptures
Background:Cardiovascular disease is a leading cause of death worldwide, claiming the lives of an estimated 17 million people annually. Myocardial infarctions (MI), or heart attacks, are a leading cause of mortality and morbidity. Complications following MI include maladaptive left ventricle (LV) tissue remodeling and cardiac rupture. Cardiac rupture...
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