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Search Term: peptides
Technologies
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High Affinity RHAMM/HMMR Binding
Peptides for Imaging and Therapeutic Applications
BackgroundHyaluronan (HA) is a simple extracellular matrix polysaccharide that a wealth of experimental approaches has demonstrated actively regulates inflammation in tissue repair, fibrogenic disease processes and cancer progression. In general, large HA polymers, which are mainly present in homeostatic tissues, are immunologically quiescent and contribute...
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Peptides targeting EGFL7, a critical player in angiogenesis
Background:Epidermal growth factor-like 7 (EGFL7) is an endothelial cell secreted protein whose expression is restricted to actively remodeling vascular endothelium. It is critical for vascular tube formation during angiogenesis through localizing to the extracellular matrix (ECM) at the basal surface of endothelial cells and promoting endothelial cell...
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